Gene, Cell and Tissue

Published by: Kowsar

Association of Arg462Gln Polymorphism in RNASEL Gene With the Risk of Prostate CancerAmong Iranian Population

Roshni Roy 1 , * and Bidyut Roy 1
Authors Information
1 Unit of Human Genetics, Indian Statistical Institute, Kolkata, India
Article information
  • Gene, Cell and Tissue: January 01, 2015, 2 (1); e23733
  • Published Online: December 25, 2014
  • Article Type: Letter
  • Received: September 18, 2014
  • Revised: October 12, 2014
  • Accepted: October 14, 2014
  • DOI: 10.17795/gct-23733

To Cite: Roy R, Roy B. Association of Arg462Gln Polymorphism in RNASEL Gene With the Risk of Prostate CancerAmong Iranian Population, Gene Cell Tissue. 2015 ; 2(1):e23733. doi: 10.17795/gct-23733.

Copyright © 2014, Zahedan University of Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
Footnote
References
  • 1. Muendlein A, Lang AH. R462Q Mutation in Prostate Cancer Specimens. Gene Cell Tissue 2014; 1(3)
  • 2. Haas GP, Delongchamps N, Brawley OW, Wang CY, de la Roza G. The worldwide epidemiology of prostate cancer: perspectives from autopsy studies. Can J Urol. 2008; 15(1): 3866-71[PubMed]
  • 3. Lessick M, Katz A. A genetics perspective on prostate cancer. Urol Nurs. 2006; 26(6): 454-60[PubMed]
  • 4. Ostrander EA, Markianos K, Stanford JL. Finding prostate cancer susceptibility genes. Annu Rev Genomics Hum Genet. 2004; 5: 151-75[DOI][PubMed]
  • 5. Smith JR, Freije D, Carpten JD, Gronberg H, Xu J, Isaacs SD, et al. Major susceptibility locus for prostate cancer on chromosome 1 suggested by a genome-wide search. Science. 1996; 274(5291): 1371-4[PubMed]
  • 6. Carpten J, Nupponen N, Isaacs S, Sood R, Robbins C, Xu J, et al. Germline mutations in the ribonuclease L gene in families showing linkage with HPC1. Nat Genet. 2002; 30(2): 181-4[DOI][PubMed]
  • 7. Rokman A, Ikonen T, Seppala EH, Nupponen N, Autio V, Mononen N, et al. Germline alterations of the RNASEL gene, a candidate HPC1 gene at 1q25, in patients and families with prostate cancer. Am J Hum Genet. 2002; 70(5): 1299-304[DOI][PubMed]
  • 8. Casey G, Neville PJ, Plummer SJ, Xiang Y, Krumroy LM, Klein EA, et al. RNASEL Arg462Gln variant is implicated in up to 13% of prostate cancer cases. Nat Genet. 2002; 32(4): 581-3[DOI][PubMed]
  • 9. Robbins CM, Hernandez W, Ahaghotu C, Bennett J, Hoke G, Mason T, et al. Association of HPC2/ELAC2 and RNASEL non-synonymous variants with prostate cancer risk in African American familial and sporadic cases. Prostate. 2008; 68(16): 1790-7[DOI][PubMed]
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .
Readers' Comments