Gene, Cell and Tissue

Published by: Kowsar

Spectroscopic Studies on the Interaction of Anti Cancer Rosemary With ctDNA

Seyedeh Elham Mostafavinia 1 and Reyhane Hoshyar 1 , *
Authors Information
1 Department of Biochemistry, Faculty of Medicine, Birjand University of Medical Sciences, Birjand, IR Iran
Article information
  • Gene, Cell and Tissue: April 01, 2016, 3 (2); e35638
  • Published Online: February 27, 2016
  • Article Type: Research Article
  • Received: December 20, 2015
  • Revised: January 20, 2016
  • Accepted: January 20, 2016
  • DOI: 10.17795/gct-35638

To Cite: Mostafavinia S E, Hoshyar R. Spectroscopic Studies on the Interaction of Anti Cancer Rosemary With ctDNA, Gene Cell Tissue. 2016 ; 3(2):e35638. doi: 10.17795/gct-35638.

Copyright © 2016, Zahedan University of Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Materials and Methods
4. Results
5. Discussion
  • 1. Bhadoriya SS, Mangal A, Madoriya N, Dixit P. Bioavailability and bioactivity enhancement of herbal drugs by “Nanotechnology”: a review. JCPR. 2011; 8: 1-7
  • 2. Sirajuddin M, Ali S, Badshah A. Drug-DNA interactions and their study by UV-Visible, fluorescence spectroscopies and cyclic voltametry. J Photochem Photobiol B. 2013; 124: 1-19[DOI][PubMed]
  • 3. Agarwal S, Jangir DK, Mehrotra R. Spectroscopic studies of the effects of anticancer drug mitoxantrone interaction with calf-thymus DNA. J Photochem Photobiol B. 2013; 120: 177-82[DOI][PubMed]
  • 4. Nafisi S, Adelzadeh M, Norouzi Z, Sarbolouki MN. Curcumin binding to DNA and RNA. DNA Cell Biol. 2009; 28(4): 201-8[DOI][PubMed]
  • 5. Sun H, Tang Y, Xiang J, Xu G, Zhang Y, Zhang H, et al. Spectroscopic studies of the interaction between quercetin and G-quadruplex DNA. Bioorg med chem letters. 2006; 16(13): 3586-9
  • 6. Bathaie SZ, Bolhasani A, Hoshyar R, Ranjbar B, Sabouni F, Moosavi-Movahedi AA. Interaction of saffron carotenoids as anticancer compounds with ctDNA, Oligo (dG.dC)15, and Oligo (dA.dT)15. DNA Cell Biol. 2007; 26(8): 533-40[DOI][PubMed]
  • 7. Hoshyar R, Bathaie SZ, Ashrafi M. Interaction of safranal and picrocrocin with ctDNA and their preferential mechanisms of binding to GC- and AT-rich oligonucleotides. DNA Cell Biol. 2008; 27(12): 665-73[DOI][PubMed]
  • 8. Oluwatuyi M, Kaatz GW, Gibbons S. Antibacterial and resistance modifying activity of Rosmarinus officinalis. Phytochemistry. 2004; 65(24): 3249-54[DOI][PubMed]
  • 9. Zegura B, Dobnik D, Niderl MH, Filipic M. Antioxidant and antigenotoxic effects of rosemary (Rosmarinus officinalis L.) extracts in Salmonella typhimurium TA98 and HepG2 cells. Environ Toxicol Pharmacol. 2011; 32(2): 296-305[DOI][PubMed]
  • 10. Tai J, Cheung S, Wu M, Hasman D. Antiproliferation effect of Rosemary (Rosmarinus officinalis) on human ovarian cancer cells in vitro. Phytomedicine. 2012; 19(5): 436-43[DOI][PubMed]
  • 11. Yan M, Li G, Patiwala SM, Householter E, Johnson JJ. Anti-cancer activity of rosemary extract in colon cancer cells: Involvement of Nrf2 and ERK pathways. Cancer Res. 2014; 74(19 Supplement): 4122
  • 12. Kang J, Wu H, Lu X, Wang Y, Zhou L. Study on the interaction of new water-soluble porphyrin with DNA. Spectrochim Acta A Mol Biomol Spectrosc. 2005; 61(9): 2041-7[DOI][PubMed]
  • 13. Chang YM, Chen CK, Hou MH. Conformational changes in DNA upon ligand binding monitored by circular dichroism. Int J Mol Sci. 2012; 13(3): 3394-413[DOI][PubMed]
  • 14. Hoshyar R, Mahboob Z, Zarban A. The antioxidant and chemical properties of Berberis vulgaris and its cytotoxic effect on human breast carcinoma cells. Cytotechnology. 2015; [DOI][PubMed]
  • 15. Palchaudhuri R, Hergenrother PJ. DNA as a target for anticancer compounds: methods to determine the mode of binding and the mechanism of action. Curr Opin Biotechnol. 2007; 18(6): 497-503[DOI][PubMed]
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