Gene, Cell and Tissue

Published by: Kowsar

The Relationship Between Polymorphisms of FTO Gene and Type 2 Diabetes Mellitus

Sayed Alireza Mirsane 1 , 2 , * , Shima Shafagh 3 and Nasrin Oraei 4
Authors Information
1 Genetic Sciences Student and Researcher, University Complex, Qom, IR Iran
2 Surgical Technologist, Kashan University of Medical Sciences, Kashan, IR Iran
3 General Surgery Specialist, Medical School, Kashan University of Medical Sciences, Kashan, IR Iran
4 Lecturer of Education Office, Esfahan, IR Iran
Article information
  • Gene, Cell and Tissue: April 2017, 4 (2); e42028
  • Published Online: November 14, 2016
  • Article Type: Letter
  • Received: September 3, 2016
  • Revised: November 7, 2016
  • Accepted: November 8, 2016
  • DOI: 10.5812/gct.42028

To Cite: Mirsane S A, Shafagh S, Oraei N. The Relationship Between Polymorphisms of FTO Gene and Type 2 Diabetes Mellitus, Gene Cell Tissue. 2017 ; 4(2):e42028. doi: 10.5812/gct.42028.

Copyright © 2016, Zahedan University of Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
References
  • 1. Yang L, Shao J, Bian Y, Wu H, Shi L, Zeng L, et al. Prevalence of type 2 diabetes mellitus among inland residents in China (2000-2014): A meta-analysis. J Diabetes Investig. 2016; 7(6): 845-52[DOI][PubMed]
  • 2. O'Neil PM, Miller-Kovach K, Tuerk PW, Becker LE, Wadden TA, Fujioka K, et al. Randomized controlled trial of a nationally available weight control program tailored for adults with type 2 diabetes. Obesity (Silver Spring). 2016; 24(11): 2269-77[DOI][PubMed]
  • 3. Scuteri A, Sanna S, Chen WM, Uda M, Albai G, Strait J, et al. Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits. PLoS Genet. 2007; 3(7): 115[DOI][PubMed]
  • 4. Loos RJ, Yeo GS. The bigger picture of FTO: the first GWAS-identified obesity gene. Nat Rev Endocrinol. 2014; 10(1): 51-61[DOI][PubMed]
  • 5. Horikoshi M, Hara K, Ito C, Shojima N, Nagai R, Ueki K, et al. Variations in the HHEX gene are associated with increased risk of type 2 diabetes in the Japanese population. Diabetologia. 2007; 50(12): 2461-6[DOI][PubMed]
  • 6. Bakhshi Ganje M, Sheykhha MH, Farashahi E, Mohammadzade M. Association of rs16953002 FTO Gene Polymorphism with Type 2 Diabetes and Obesity. J Fasa Univ Med Sci. 2016; 6(1): 27-34
  • 7. Song Y, You NC, Hsu YH, Howard BV, Langer RD, Manson JE, et al. FTO polymorphisms are associated with obesity but not diabetes risk in postmenopausal women. Obesity (Silver Spring). 2008; 16(11): 2472-80[DOI][PubMed]
  • 8. Ramya K, Radha V, Ghosh S, Majumder PP, Mohan V. Genetic variations in the FTO gene are associated with type 2 diabetes and obesity in south Indians (CURES-79). Diabetes Technol Ther. 2011; 13(1): 33-42[DOI][PubMed]
  • 9. Niyazy MM. The Role of FAT MASS and Obesity Association Locus" Fto" Gene Polymorphism in Susceptibility to Development of Type 2 Diabetes and Obesity in Selected Sudanese Population. 2015;
  • 10. Prakash J, Srivastava N, Awasthi S, Agarwal CG, Natu SM, Rajpal N, et al. Association of FTO rs17817449 SNP with obesity and associated physiological parameters in a north Indian population. Ann Hum Biol. 2011; 38(6): 760-3[DOI][PubMed]
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

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