Gene, Cell and Tissue

Published by: Kowsar

ER and PR Positive, or Her2 Negative Tumor of rs2363956 and rs3803662 GWAS in Breast Cancer

Ashkan Alborzi 1 , Massoud Houshmand 2 and Mojgan Hosseini 1 , *
Authors Information
1 Department of Science, Islamshahr Branch, Islamic Azad University, Islamshahr, Tehran, IR Iran
2 National Institute for Genetic Engineering and Biotechnology (NIGEB), Tehran, IR Iran
Article information
  • Gene, Cell and Tissue: October 2017, 4 (4); e63407
  • Published Online: October 31, 2017
  • Article Type: Research Article
  • Received: August 20, 2017
  • Revised: September 22, 2017
  • Accepted: October 19, 2017
  • DOI: 10.5812/gct.63407

To Cite: Alborzi A, Houshmand M, Hosseini M. ER and PR Positive, or Her2 Negative Tumor of rs2363956 and rs3803662 GWAS in Breast Cancer, Gene Cell Tissue. 2017 ; 4(4):e63407. doi: 10.5812/gct.63407.

Abstract
Copyright © 2017, Gene, Cell and Tissue. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited
1. Background
2. Methods
3. Results
4. Discussion
Acknowledgements
References
  • 1. Easton DF, Pooley KA, Dunning AM, Pharoah PD, Thompson D, Ballinger DG, et al. Genome-wide association study identifies novel breast cancer susceptibility loci. Nature. 2007;447(7148):1087-93. doi: 10.1038/nature05887. [PubMed: 17529967].
  • 2. Stacey SN, Manolescu A, Sulem P, Thorlacius S, Gudjonsson SA, Jonsson GF, et al. Common variants on chromosome 5p12 confer susceptibility to estrogen receptor-positive breast cancer. Nat Genet. 2008;40(6):703-6. doi: 10.1038/ng.131. [PubMed: 18438407].
  • 3. Silva Idos S, De Stavola B, McCormack V, Collaborative Group on Pre-Natal Risk F, Subsequent Risk of Breast C. Birth size and breast cancer risk: re-analysis of individual participant data from 32 studies. PLoS Med. 2008;5(9). e193. doi: 10.1371/journal.pmed.0050193. [PubMed: 18828667].
  • 4. Pabalan N, Jarjanazi H, Sung L, Li H, Ozcelik H. Menopausal status modifies breast cancer risk associated with the myeloperoxidase (MPO) G463A polymorphism in Caucasian women: a meta-analysis. PLoS One. 2012;7(3). e32389. doi: 10.1371/journal.pone.0032389. [PubMed: 22427832].
  • 5. Hunter DJ, Kraft P, Jacobs KB, Cox DG, Yeager M, Hankinson SE, et al. A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer. Nat Genet. 2007;39(7):870-4. doi: 10.1038/ng2075. [PubMed: 17529973].
  • 6. Haiman CA, Patterson N, Freedman ML, Myers SR, Pike MC, Waliszewska A, et al. Multiple regions within 8q24 independently affect risk for prostate cancer. Nat Genet. 2007;39(5):638-44. doi: 10.1038/ng2015. [PubMed: 17401364].
  • 7. Tamimi RM, Lagiou P, Czene K, Liu J, Ekbom A, Hsieh CC, et al. Birth weight, breast cancer susceptibility loci, and breast cancer risk. Cancer Causes Control. 2010;21(5):689-96. doi: 10.1007/s10552-009-9496-7. [PubMed: 20054709].
  • 8. Lichtenstein P, Holm NV, Verkasalo PK, Iliadou A, Kaprio J, Koskenvuo M, et al. Environmental and heritable factors in the causation of cancer--analyses of cohorts of twins from Sweden, Denmark, and Finland. N Engl J Med. 2000;343(2):78-85. doi: 10.1056/NEJM200007133430201. [PubMed: 10891514].
  • 9. Ferlay J, Soerjomataram I, Dikshit R, Eser S, Mathers C, Rebelo M, et al. Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012. Int J Cancer. 2015;136(5):E359-86. doi: 10.1002/ijc.29210. [PubMed: 25220842].
  • 10. Han W, Woo JH, Yu JH, Lee MJ, Moon HG, Kang D, et al. Common genetic variants associated with breast cancer in Korean women and differential susceptibility according to intrinsic subtype. Cancer Epidemiol Biomarkers Prev. 2011;20(5):793-8. doi: 10.1158/1055-9965.EPI-10-1282. [PubMed: 21415360].
  • 11. Xiang Z, Xu M, Liao M, Jiang Y, Jiang Q, Feng R, et al. Integrating Genome-Wide Association Study and Brain Expression Data Highlights Cell Adhesion Molecules and Purine Metabolism in Alzheimer's Disease. Mol Neurobiol. 2015;52(1):514-21. doi: 10.1007/s12035-014-8884-5. [PubMed: 25204495].
  • 12. Harlid S, Ivarsson MI, Butt S, Grzybowska E, Eyfjord JE, Lenner P, et al. Combined effect of low-penetrant SNPs on breast cancer risk. Br J Cancer. 2012;106(2):389-96. doi: 10.1038/bjc.2011.461. [PubMed: 22045194].
  • 13. Chen YC, Hunter DJ. Molecular epidemiology of cancer. CA Cancer J Clin. 2005;55(1):45-54. quiz 57. [PubMed: 15661686].
  • 14. Song H, Ramus SJ, Tyrer J, Bolton KL, Gentry-Maharaj A, Wozniak E, et al. A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2. Nat Genet. 2009;41(9):996-1000. doi: 10.1038/ng.424. [PubMed: 19648919].
  • 15. Bolton KL, Tyrer J, Song H, Ramus SJ, Notaridou M, Jones C, et al. Common variants at 19p13 are associated with susceptibility to ovarian cancer. Nat Genet. 2010;42(10):880-4. doi: 10.1038/ng.666. [PubMed: 20852633].
  • 16. Liang J, Chen P, Hu Z, Shen H, Wang F, Chen L, et al. Genetic variants in trinucleotide repeat-containing 9 (TNRC9) are associated with risk of estrogen receptor positive breast cancer in a Chinese population. Breast Cancer Res Treat. 2010;124(1):237-41. doi: 10.1007/s10549-010-0809-z. [PubMed: 20213080].
  • 17. Mizoo T, Taira N, Nishiyama K, Nogami T, Iwamoto T, Motoki T, et al. Effects of lifestyle and single nucleotide polymorphisms on breast cancer risk: a case-control study in Japanese women. BMC Cancer. 2013;13:565. doi: 10.1186/1471-2407-13-565. [PubMed: 24289300].
  • 18. Elematore I, Gonzalez-Hormazabal P, Reyes JM, Blanco R, Bravo T, Peralta O, et al. Association of genetic variants at TOX3, 2q35 and 8q24 with the risk of familial and early-onset breast cancer in a South-American population. Mol Biol Rep. 2014;41(6):3715-22. doi: 10.1007/s11033-014-3236-0. [PubMed: 24532140].
  • 19. Gorodnova TV, Kuligina E, Yanus GA, Katanugina AS, Abysheva SN, Togo AV, et al. Distribution of FGFR2, TNRC9, MAP3K1, LSP1, and 8q24 alleles in genetically enriched breast cancer patients versus elderly tumor-free women. Cancer Genet Cytogenet. 2010;199(1):69-72. doi: 10.1016/j.cancergencyto.2010.01.020. [PubMed: 20417875].
  • 20. Mellemkjaer L, Olsen ML, Sorensen HT, Thulstrup AM, Olsen J, Olsen JH. Birth weight and risk of early-onset breast cancer (Denmark). Cancer Causes Control. 2003;14(1):61-4. [PubMed: 12708726].
  • 21. He Y. Relationship between five GWAS-identified single nucleotide polymorphisms and female breast cancer in the Chinese Han population. Tumor Biol. 2016;37(7):9739-44.
  • 22. Slattery ML, Baumgartner KB, Giuliano AR, Byers T, Herrick JS, Wolff RK. Replication of five GWAS-identified loci and breast cancer risk among Hispanic and non-Hispanic white women living in the Southwestern United States. Breast Cancer Res Treat. 2011;129(2):531-9. doi: 10.1007/s10549-011-1498-y. [PubMed: 21475998].
  • 23. Antoniou AC, Wang X, Fredericksen ZS, McGuffog L, Tarrell R, Sinilnikova OM, et al. A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor-negative breast cancer in the general population. Nat Genet. 2010;42(10):885-92. doi: 10.1038/ng.669. [PubMed: 20852631].
  • 24. Stevens KN, Vachon CM, Lee AM, Slager S, Lesnick T, Olswold C, et al. Common breast cancer susceptibility loci are associated with triple-negative breast cancer. Cancer Res. 2011;71(19):6240-9. doi: 10.1158/0008-5472.CAN-11-1266. [PubMed: 21844186].
  • 25. Stacey SN, Manolescu A, Sulem P, Rafnar T, Gudmundsson J, Gudjonsson SA, et al. Common variants on chromosomes 2q35 and 16q12 confer susceptibility to estrogen receptor-positive breast cancer. Nat Genet. 2007;39(7):865-9. doi: 10.1038/ng2064. [PubMed: 17529974].
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