Gene, Cell and Tissue

Published by: Kowsar

Association of PvuII T> C and XbaI A> G Polymorphisms of Estrogen Receptor α Gene with Uterine Leiomyoma: A Case-Control Study

Mojgan Mokhtari 1 , Sepideh Zakerian 2 , Farzaneh Farajian-Mashhadi 3 , 4 and Saeedeh Salimi 5 , *
Authors Information
1 Department of Obstetrics and Gynecology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran
2 Department of Obstetrics and Gynecology, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran
3 Department of Pharmacology, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran
4 Cellular and Molecular Research Center, Zahedan University of Medical Sciences, Zahedan, Iran
5 Department of Clinical Biochemistry, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran
Article information
  • Gene, Cell and Tissue: April 2018, 5 (2); e79616
  • Published Online: August 8, 2018
  • Article Type: Research Article
  • Received: May 23, 2018
  • Revised: July 31, 2018
  • Accepted: August 4, 2018
  • DOI: 10.5812/ijhrba.79616

To Cite: Mokhtari M, Zakerian S, Farajian-Mashhadi F, Salimi S. Association of PvuII T> C and XbaI A> G Polymorphisms of Estrogen Receptor α Gene with Uterine Leiomyoma: A Case-Control Study, Gene Cell Tissue. 2018 ; 5(2):e79616. doi: 10.5812/ijhrba.79616.

Abstract
Copyright © 2018, Gene, Cell and Tissue. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited
1. Background
2. Methods
3. Results
4. Discussion
Footnote
References
  • 1. Hoffman B, Schorge J, Schaffer J, Halvorson L, Bradshaw K, Cunningham F. Williams gynecology. 2 ed. Mcgraw-hill; 2012.
  • 2. Jeon YT, Kim JW, Park NH, Song YS, Kang SB, Lee HP. DNA repair gene XRCC1 Arg399Gln polymorphism is associated with increased risk of uterine leiomyoma. Hum Reprod. 2005;20(6):1586-9. doi: 10.1093/humrep/deh836. [PubMed: 15760950].
  • 3. Parker WH. Etiology, symptomatology, and diagnosis of uterine myomas. Fertil Steril. 2007;87(4):725-36. doi: 10.1016/j.fertnstert.2007.01.093. [PubMed: 17430732].
  • 4. Wallach EE, Buttram VC, Reiter RC. Uterine leiomyomata: etiology, symptomatology, and management. Fertil Steril. 1981;36(4):433-45. doi: 10.1016/s0015-0282(16)45789-4.
  • 5. Hodges LC, Bergerson JS, Hunter DS, Walker CL. Estrogenic effects of organochlorine pesticides on uterine leiomyoma cells in vitro. Toxicol Sci. 2000;54(2):355-64. [PubMed: 10774817].
  • 6. Parker WH, Fu YS, Berek JS. Uterine sarcoma in patients operated on for presumed leiomyoma and rapidly growing leiomyoma. Obstet Gynecol. 1994;83(3):414-8. [PubMed: 8127535].
  • 7. Speroff L, Fritz MA. Clinical gynecologic endocrinology and infertility. lippincott Williams & wilkins; 2005.
  • 8. Thompson JD, Rock JA. Leiomyomata uteri and myomectomy. In: Rock JA, Thompson JD, editors. Te Linde’s operative gynecology. 8 ed. Philadelphia: Lippincott-Raven; 1997. p. 731-70.
  • 9. Thomas M, Kalita A, Labrecque S, Pim D, Banks L, Matlashewski G. Two polymorphic variants of wild-type p53 differ biochemically and biologically. Mol Cell Biol. 1999;19(2):1092-100. [PubMed: 9891044]. [PubMed Central: PMC116039].
  • 10. Gibbs RS, Danforth DN. Danforth's obstetrics and gynecology. China: Lippincott Williams & Wilkins; 2008.
  • 11. Kos M, Reid G, Denger S, Gannon F. Minireview: genomic organization of the human ERalpha gene promoter region. Mol Endocrinol. 2001;15(12):2057-63. doi: 10.1210/mend.15.12.0731. [PubMed: 11731608].
  • 12. Zuppan PJ, Hall J, Ponglikitmongkol M, Spielman R, King M. Polymorphisms at the estroten receptor (ESR) locus and linkage relation-ships on chromosome 6q. Cytegenet. Cell Genet. 1989;51:1116.
  • 13. Salimi S, Mohammadpour-Gharehbagh A, Keshavarzi F, Farajian-Mashhadi F, Mousavi M, Sandoughi M. Association between ERalpha polymorphisms and systemic lupus erythematosus: susceptibility and in silico analysis. Int J Rheum Dis. 2018;21(1):214-22. doi: 10.1111/1756-185X.13230. [PubMed: 29356461].
  • 14. Kitawaki J, Obayashi H, Ishihara H, Koshiba H, Kusuki I, Kado N, et al. Oestrogen receptor-alpha gene polymorphism is associated with endometriosis, adenomyosis and leiomyomata. Hum Reprod. 2001;16(1):51-5. [PubMed: 11139535].
  • 15. Salimi S, Hajizadeh A, Khodamian M, Pejman A, Fazeli K, Yaghmaei M. Age-dependent association of MDM2 promoter polymorphisms and uterine leiomyoma in South-East Iran: A preliminary report. J Obstet Gynaecol Res. 2015;41(5):729-34. doi: 10.1111/jog.12625. [PubMed: 25511444].
  • 16. Yaghmaei M, Salimi S, Namazi L, Farajian-Mashhadi F. Association of XRCC1 Arg399GIn and Tp53 Arg72Pro polymorphisms and increased risk of uterine leiomyoma - A case-control study. Genet Mol Biol. 2015;38(4):444-9. doi: 10.1590/S1415-475738420140359. [PubMed: 26692154]. [PubMed Central: PMC4763320].
  • 17. Aslani S, Hossein-Nezhad A, Mirzaei K, Maghbooli Z, Afshar AN, Karimi F. VDR FokI polymorphism and its potential role in the pathogenesis of gestational diabetes mellitus and its complications. Gynecol Endocrinol. 2011;27(12):1055-60. doi: 10.3109/09513590.2011.569786. [PubMed: 21663527].
  • 18. Kumazaki K, Nakayama M, Suehara N, Wada Y. Expression of vascular endothelial growth factor, placental growth factor, and their receptors Flt-1 and KDR in human placenta under pathologic conditions. Hum Pathol. 2002;33(11):1069-77. doi: 10.1053/hupa.2002.129420. [PubMed: 12454810].
  • 19. Al-Hendy A, Salama S. Gene therapy and uterine leiomyoma: a review. Hum Reprod Update. 2006;12(4):385-400. doi: 10.1093/humupd/dml015. [PubMed: 16603566].
  • 20. Hsieh YY, Wang YK, Chang CC, Lin CS. Estrogen receptor alpha-351 XbaI*G and -397 PvuII*C-related genotypes and alleles are associated with higher susceptibilities of endometriosis and leiomyoma. Mol Hum Reprod. 2007;13(2):117-22. doi: 10.1093/molehr/gal099. [PubMed: 17121748].
  • 21. Orsted DD, Bojesen SE, Tybjaerg-Hansen A, Nordestgaard BG. Tumor suppressor p53 Arg72Pro polymorphism and longevity, cancer survival, and risk of cancer in the general population. J Exp Med. 2007;204(6):1295-301. doi: 10.1084/jem.20062476. [PubMed: 17535973]. [PubMed Central: PMC2118619].
  • 22. Salimi S, Farajian-Mashhadi F, Tabatabaei E, Shahrakipour M, Yaghmaei M, Mokhtari M. Estrogen receptor alpha XbaI GG genotype was associated with severe preeclampsia. Clin Exp Hypertens. 2017;39(3):220-4. doi: 10.1080/10641963.2016.1235182. [PubMed: 28448182].
  • 23. Massart F, Becherini L, Marini F, Noci I, Piciocchi L, Del Monte F, et al. Analysis of estrogen receptor (ERα and ERß) and progesterone receptor (PR) polymorphisms in uterine leiomyomas. Med Sci Monitor. 2003;9(1):BR25-30.
  • 24. Denschlag D, Bentz EK, Hefler L, Pietrowski D, Zeillinger R, Tempfer C, et al. Genotype distribution of estrogen receptor-alpha, catechol-O-methyltransferase, and cytochrome P450 17 gene polymorphisms in Caucasian women with uterine leiomyomas. Fertil Steril. 2006;85(2):462-7. doi: 10.1016/j.fertnstert.2005.07.1308. [PubMed: 16595228].
  • 25. Villanova FE, Andrade PM, Otsuka AY, Gomes MT, Leal ES, Castro RA, et al. Estrogen receptor alpha polymorphism and susceptibility to uterine leiomyoma. Steroids. 2006;71(11-12):960-5. doi: 10.1016/j.steroids.2006.07.005. [PubMed: 16935316].
  • 26. Al-Hendy A, Salama SA. Ethnic distribution of estrogen receptor-alpha polymorphism is associated with a higher prevalence of uterine leiomyomas in black Americans. Fertil Steril. 2006;86(3):686-93. doi: 10.1016/j.fertnstert.2006.01.052. [PubMed: 16860797].
  • 27. Govindan S, Shaik NA, Vedicherla B, Kodati V, Rao KP, Hasan Q. Estrogen receptor-alpha gene (T/C) Pvu II polymorphism in endometriosis and uterine fibroids. Dis Markers. 2009;26(4):149-54. doi: 10.3233/DMA-2009-0625. [PubMed: 19729795]. [PubMed Central: PMC3833240].
  • 28. Feng Y, Lin X, Zhou S, Xu N, Yi T, Zhao X. The associations between the polymorphisms of the ER-alpha gene and the risk of uterine leiomyoma (ULM). Tumour Biol. 2013;34(5):3077-82. doi: 10.1007/s13277-013-0874-0. [PubMed: 23749503].
  • 29. Taghizade Mortezaee F, Tabatabaiefar MA, Hashemzadeh Chaleshtori M, Miraj S. Lack of Association between ESR1 and CYP1A1 Gene Polymorphisms and Susceptibility to Uterine Leiomyoma in Female Patients of Iranian Descent. Cell J. 2014;16(2):225-30. [PubMed: 24567938]. [PubMed Central: PMC4072073].
  • 30. Veronica M, Ali A, Venkateshwari A, Mamata D, Nallari P. Association of estrogen and progesterone receptor gene polymorphisms and their respective hormones in uterine leiomyomas. Tumour Biol. 2016;37(6):8067-74. doi: 10.1007/s13277-015-4711-5. [PubMed: 26715264].
  • 31. Huang Y, Wright SI, Agrawal AF. Genome-wide patterns of genetic variation within and among alternative selective regimes. PLoS Genet. 2014;10(8). e1004527. doi: 10.1371/journal.pgen.1004527. [PubMed: 25101783]. [PubMed Central: PMC4125100].

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